Our Drug Development Programs

Multiple Application Targeting Platform

Soricimed has developed a novel platform consisting of a number of proprietary peptides that target a specific calcium ion channel, TRPV6. Our novel peptides target and bind to TRPV6, resulting in the ability to act as a primary targeted therapeutic or as delivery ligands for other anti-cancer payloads. When used as a delivery ligand, our targeting peptides can deliver other anti-cancer agents directly and rapidly to the cancer cells. This method of delivery can:

  • Be less harmful to healthy cells
  • Have fewer side effects
  • Be more effective in killing cancer cells

Applications of our platform currently include Radioligand Therapies that provide precise delivery of a therapeutic radioisotope directly to tumors, and Peptide-Drug Conjugates (PDC’s) that deliver potent cancer-killing payloads directly to tumors.

How our targeting ligands works

Soricimed’s targeting ligands are proprietary synthetic peptides. These peptide ligands bind to TRPV6 – a calcium ion channel that is overexpressed in cancer cells. Cancers where TRVP6 becomes over-expressed include prostate, pancreatic, ovarian, breast, uterine, colon, and certain other solid tumor cancers.

Illustration of an enlarged prostate with cancerous cells growing. 

Enlarged Prostate

Prostate cancer is one of many solid tumour cancers where TRVP6 becomes over-expressed.

Soricimed’s peptide ligands:

  • Target and bind to the overexpressed TRVP6 in cancer cells at high affinity and specificity. These ligands can selectively target cells that over express TRVP6, bind to them, and then deliver anti-cancer payloads such as radioisotopes and anticancer drugs.
  • Through this property of selective binding to cancer cells, the payloads are delivered in a targeted manner thus optimizing efficiency and reducing off target toxicity. 

Learn how our TRPV6-targeting peptide platform works

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